Table 4 Hypermethylated annotations in slow-cleavage embryos
Term | Number of genes hypermethylated | P value |
|---|---|---|
Biological process | ||
Phosphorus metabolic process | 55 | 2.66E−02 |
RNA processing | 27 | 2.10E−02 |
Regulation of small GTPase-mediated signal transduction | 24 | 2.89E−04 |
Generation of precursor metabolites and energy | 20 | 8.53E−02* |
Regulation of Ras protein signal transduction | 18 | 2.82E−03 |
Chordate embryonic development | 17 | 5.94E−02* |
Cellular component morphogenesis | 15 | 3.13E−02 |
Secretion | 14 | 4.17E−02 |
Cellular proliferation | 13 | 5.25E−02 |
Blastocyst development | 8 | 5.14E−03 |
Cellular component | ||
Plasma membrane | 88 | 1.57E−02 |
Mitochondrion | 58 | 1.74E−02 |
Endoplasmatic reticulum | 34 | 9.59E−02* |
Golgi apparatus | 14 | 4.16 E−02 |
Spliceosome | 10 | 2.77 E−02 |
Molecular function | ||
Nucleotide biding | 135 | 9.46E−04 |
ATP biding | 84 | 1.53E−02 |
Protein kinase activity | 44 | 2.11E−03 |
GTPase regulator activity | 30 | 8.52E−05 |
FAD biding | 9 | 1.79E−02 |