Table 3 Hypermethylated annotations in fast-cleavage embryos
Term | Number of genes hypermethylated | P value |
|---|---|---|
Biological process | ||
Phosphate metabolic process | 134 | 2.21E−09 |
Intracellular signaling cascade | 83 | 6.16E−03 |
Ionic transport | 80 | 3.08E−02 |
Macromolecule catabolic process | 55 | 2.22E−02 |
Regulation of programmed cell death | 51 | 2.06E−02 |
Regulation of cell proliferation | 47 | 2.69E−02 |
Regulation of small GTPase-mediated signal transduction | 43 | 3.40E−06 |
Cytoskeleton organization | 29 | 7.01E−02* |
Cellular component morphogenesis | 25 | 2.48E−02 |
Fatty acid metabolic process | 21 | 7.84E−03 |
Cellular components | ||
Plasma membrane | 171 | 2.30E−03 |
Organelle lumen | 88 | 9.56E−03 |
Endoplasmic reticulum | 65 | 4.48E−02 |
Golgi apparatus | 61 | 6.39E−03 |
Cytosol | 50 | 2.61E−03 |
Molecular function | ||
Ion biding | 388 | 7.47E−06 |
Nucleotide biding | 273 | 3.13E−06 |
ATP biding | 199 | 2.58E−09 |
Protein kinase activity | 102 | 9.08E−10 |
RNA biding | 57 | 5.78E−02 |