|
Demethylating TF
|
Prom-associated
|
Prom-nonassociated
|
All demethyl
|
% of Prom-associated
|
p value (Fisher’s exact test)
|
|---|
|
RUNX3
|
114
|
1005
|
1119
|
10.19
|
1.93E−10
|
|
GATA2
|
47
|
192
|
239
|
19.67
|
1.51E−14
|
|
CEBPB
|
119
|
670
|
789
|
15.08
|
2.20E−16
|
|
MAFB
|
46
|
219
|
265
|
17.36
|
3.00E−12
|
|
NR4A2
|
79
|
474
|
553
|
14.29
|
6.22E−15
|
|
MYOD1
|
135
|
836
|
971
|
13.90
|
2.20E−16
|
|
CEBPA
|
79
|
710
|
789
|
10.01
|
2.21E−07
|
|
TBX5
|
212
|
1629
|
1841
|
11.52
|
2.20E−16
|
|
SPI1
|
190
|
930
|
1120
|
16.96
|
2.20E−16
|
|
RUNX1
|
27
|
143
|
170
|
15.88
|
5.23E−07
|
|
All probes
|
26,234
|
459,051
|
485,285
|
5.41
| |
- “Prom-associated” and “Prom-nonassociated” indicate the number of promoter-associated CpGs and nonpromoter-associated CpG, respectively. “All dimethyl” means total number of demethylated CpGs. p value represents the significance of overrepresentation of promoter-associated CpGs
