Skip to main content

Table 3 Number of promoter-associated demethylated CpGs

From: A screening system to identify transcription factors that induce binding site-directed DNA demethylation

Demethylating TF

Prom-associated

Prom-nonassociated

All demethyl

% of Prom-associated

p value (Fisher’s exact test)

RUNX3

114

1005

1119

10.19

1.93E−10

GATA2

47

192

239

19.67

1.51E−14

CEBPB

119

670

789

15.08

2.20E−16

MAFB

46

219

265

17.36

3.00E−12

NR4A2

79

474

553

14.29

6.22E−15

MYOD1

135

836

971

13.90

2.20E−16

CEBPA

79

710

789

10.01

2.21E−07

TBX5

212

1629

1841

11.52

2.20E−16

SPI1

190

930

1120

16.96

2.20E−16

RUNX1

27

143

170

15.88

5.23E−07

All probes

26,234

459,051

485,285

5.41

 
  1. “Prom-associated” and “Prom-nonassociated” indicate the number of promoter-associated CpGs and nonpromoter-associated CpG, respectively. “All dimethyl” means total number of demethylated CpGs. p value represents the significance of overrepresentation of promoter-associated CpGs
Back to article page

Epigenetics & Chromatin

ISSN: 1756-8935