Skip to main content

Advertisement

Table 3 Number of promoter-associated demethylated CpGs

From: A screening system to identify transcription factors that induce binding site-directed DNA demethylation

Demethylating TF Prom-associated Prom-nonassociated All demethyl % of Prom-associated p value (Fisher’s exact test)
RUNX3 114 1005 1119 10.19 1.93E−10
GATA2 47 192 239 19.67 1.51E−14
CEBPB 119 670 789 15.08 2.20E−16
MAFB 46 219 265 17.36 3.00E−12
NR4A2 79 474 553 14.29 6.22E−15
MYOD1 135 836 971 13.90 2.20E−16
CEBPA 79 710 789 10.01 2.21E−07
TBX5 212 1629 1841 11.52 2.20E−16
SPI1 190 930 1120 16.96 2.20E−16
RUNX1 27 143 170 15.88 5.23E−07
All probes 26,234 459,051 485,285 5.41  
  1. “Prom-associated” and “Prom-nonassociated” indicate the number of promoter-associated CpGs and nonpromoter-associated CpG, respectively. “All dimethyl” means total number of demethylated CpGs. p value represents the significance of overrepresentation of promoter-associated CpGs
Back to article page