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Fig. 5 | Epigenetics & Chromatin

Fig. 5

From: Co-regulation of transcription by BRG1 and BRM, two mutually exclusive SWI/SNF ATPase subunits

Fig. 5

Occupancy and transcriptional changes associated with BRG1 or BRM loss. a–d Effect of BRG1 or BRM depletion of BRG (a, b) or BRM (c, d). e, f Classification of ChIP-seq peaks based on loss of BRG and BRM. g, h Quantification of gene expression changes in categories assigned in e, f. Asterisk denotes p value < 0.05 by Wilcoxon rank sum test against hypothesis of no change in expression. i, j Fraction of peaks in each category associated with significantly altered gene expression. Asterisks denote p value < 0.05 by Chi-square test relative to genes that were not associated with a BRG/BRM altered peak

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