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Fig. 2 | Epigenetics & Chromatin

Fig. 2

From: Subtracting the sequence bias from partially digested MNase-seq data reveals a general contribution of TFIIS to nucleosome positioning

Fig. 2

Naked DNA correction promotes standardization of fragile nucleosomes. a The metagene analysis of nucleosomal occupancy in 1856 genes that contained a fragile − 1 nucleosome, according to [17]. Genes were scaled to the same length and then aligned to their TSS. The purple arrow indicates the expected position of fragile nucleosomes. b The metagene analysis of nucleosomal occupancy in 2872 genes that contained a stable − 1 nucleosome, according to [17]. c The metagene analysis of nucleosomal occupancy in RP genes. d A comparison of the effect of the naked DNA correction on the detection of histone and non-histone MNase-sensitive particles, according to the data from [43]

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