Skip to main content
Fig. 4 | Epigenetics & Chromatin

Fig. 4

From: Ubiquitin C-terminal hydrolase isozyme L1 is associated with shelterin complex at interstitial telomeric sites

Fig. 4

UCHL1 localizes to telomeric repeat sequences as do TRF1 and TRF2. a The top five motifs were identified using the MEME software. The E value is the expected number of hits by chance (the lower the E value the more significant is the motif). b Signal tracks showing DNA enrichment in UCHL1 ChIP from DU 145 and HEK293T cells and TRF1 or TRF2 ChIP from BJHELTRasmc cells (Simonet et al. [21]—21423270) were aligned for CLIC6 and FAM157A genes. Cells were treated with formaldehyde (1-DU 145 Input and UCHL1, HEK Input and UCHL1) or DSP/formaldehyde (2-DU 145 Input and UCHL1)

Back to article page