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Fig. 1 | Epigenetics & Chromatin

Fig. 1

From: Ubiquitin C-terminal hydrolase isozyme L1 is associated with shelterin complex at interstitial telomeric sites

Fig. 1

UCHL1 is associated with genomic DNA in prostate cancer cells expressing it. a DNA cross-linked proteins from BPH-1, DU 145, PC-3 and LNCaP cells treated with 1 mM cisplatin were electrophoretically resolved on two-dimensional PAGE. The gels were stained with silver. b–e Total cellular proteins (TCP) or DNA cross-linked proteins isolated by hydroxyapatite column chromatography from cells treated with 1 mM cisplatin or 1% formaldehyde were resolved by SDS-10% PAGE and immunoblotted with indicated antibodies. Cells in b–d were BPH-1 (B), DU 145 (D), PC-3 (P) and LNCaP (L)

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