Skip to main content

Table 3 TFs with binding sites enriched in both E1 and E2 enhancer sets

From: Genome-wide profiling of transcribed enhancers during macrophage activation

TF Mean TPM in M(IFN-γ) % Enhancers in M(IFN-γ) Mean TPM in M(IL-4/IL-13) % Enhancers in M(IL-4/IL-13) Ratio
Stat1 726.3 40.9 218.6 22.9 1.8
Irf1 1345.4 44.3 426.7 26.7 1.7
Ets1 1.4 39.1 7 25.2 1.6
Jun 74.3 14.8 70 9.9 1.5
Rela 131.6 42.6 102.8 29.8 1.4
Atf4 277.3 33.9 208.3 27.5 1.2
Junb 122 13 99.7 13 1
Irf4 2.3 13 18.7 13.7 0.9
Spi1 766.3 52.2 681.7 56.5 0.9
Cebpb 424.6 51.3 262.9 59.5 0.9
Atf3 233.9 9.6 242.9 12.2 0.8
  1. Columns show TF name, average expression in M(IFN-γ) and M(IL-4/IL-13) macrophages (in TPM, see “Methods”), percentage of enhancers overlapping corresponding binding sites, and a M(IFN-γ)/M(IL-4/IL-13) percentage ratio