Genome-wide profiling of transcribed enhancers during macrophage activation

Table 3 TFs with binding sites enriched in both E1 and E2 enhancer sets

TF	Mean TPM in M(IFN-γ)	% Enhancers in M(IFN-γ)	Mean TPM in M(IL-4/IL-13)	% Enhancers in M(IL-4/IL-13)	Ratio
Stat1	726.3	40.9	218.6	22.9	1.8
Irf1	1345.4	44.3	426.7	26.7	1.7
Ets1	1.4	39.1	7	25.2	1.6
Jun	74.3	14.8	70	9.9	1.5
Rela	131.6	42.6	102.8	29.8	1.4
Atf4	277.3	33.9	208.3	27.5	1.2
Junb	122	13	99.7	13	1
Irf4	2.3	13	18.7	13.7	0.9
Spi1	766.3	52.2	681.7	56.5	0.9
Cebpb	424.6	51.3	262.9	59.5	0.9
Atf3	233.9	9.6	242.9	12.2	0.8

Columns show TF name, average expression in M(IFN-γ) and M(IL-4/IL-13) macrophages (in TPM, see “Methods”), percentage of enhancers overlapping corresponding binding sites, and a M(IFN-γ)/M(IL-4/IL-13) percentage ratio

ISSN: 1756-8935