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Fig. 2 | Epigenetics & Chromatin

Fig. 2

From: Genome-wide profiling of transcribed enhancers during macrophage activation

Fig. 2

Macrophage-specific enhancer and gene expression. a Percentage of genes associated with different number of enhancers. b Expression of 4739 macrophage-specific enhancer eRNAs and 1481 associated genes. c Expression of 3928 non-macrophage-specific enhancer eRNAs and 1207 associated genes. In b and c, expression is shown in 184 macrophage and 744 non-macrophage samples; asterisks denote Wilcoxon rank sum test p value < 2.2 × 10−16. d Top 15 KEGG pathway maps significantly enriched for genes associated exclusively to macrophage-specific enhancers. e KEGG pathway maps enriched for genes associated exclusively to non-macrophage-specific enhancers with FDR < 0.05. In d and e next to the bars are the numbers of genes in the KEGG pathway covered by our gene list; dashed lines indicate FDR = 0.05

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