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Fig. 1 | Epigenetics & Chromatin

Fig. 1

From: Genome-wide profiling of transcribed enhancers during macrophage activation

Fig. 1

Macrophage enhancer–gene interactome. a Pipeline for identification of enhancers and enhancer–promoter associations. b Number and expression of genes associated with different number of enhancers. Dashed line shows median expression of genes not associated with any enhancer. c KEGG pathway maps significantly enriched for genes associated with a single enhancer, FDR < 0.05. d Top 15 KEGG pathway maps with the lowest FDR enriched for genes associated with more than 8 enhancers. In c and d next to the bars are the numbers of genes in the KEGG pathway covered by our gene list; dashed lines indicate FDR = 0.05

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