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Fig. 6 | Epigenetics & Chromatin

Fig. 6

From: H2A O-GlcNAcylation at serine 40 functions genomic protection in association with acetylated H2AZ or γH2AX

Fig. 6

H2AS40Gc partner changes from AcH2AZ to γH2AX during DNA damage response. a Binding of H2AS40Gc with H2A variants and Ogt in H2A3-WT and S40A-mutant mESCs during ETP treatment. These binding states were analyzed by immunoprecipitation assay using anti-Flag antibody. White arrowheads indicate exogenous H2A. Input data are shown in Additional file 1: Figure S3. b Perspective model for the dynamics of H2AS40Gc during DNA damage response

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