TY - JOUR AU - Jox, Theresa AU - Buxa, Melanie K. AU - Bohla, Dorte AU - Ullah, Ikram AU - Mačinković, Igor AU - Brehm, Alexander AU - Bartkuhn, Marek AU - Renkawitz, Rainer PY - 2017 DA - 2017/07/04 TI - Drosophila CP190- and dCTCF-mediated enhancer blocking is augmented by SUMOylation JO - Epigenetics & Chromatin SP - 32 VL - 10 IS - 1 AB - Chromatin insulators shield promoters and chromatin domains from neighboring enhancers or chromatin regions with opposing activities. Insulator-binding proteins and their cofactors mediate the boundary function. In general, covalent modification of proteins by the small ubiquitin-like modifier (SUMO) is an important mechanism to control the interaction of proteins within complexes. SN - 1756-8935 UR - https://doi.org/10.1186/s13072-017-0140-6 DO - 10.1186/s13072-017-0140-6 ID - Jox2017 ER -