Table 1 Average levels of DNA methylation on paternal and maternal alleles at the Dlk1-, IG- and Gtl2-DMRs across four developmental stages
|  |  | Dlk1-DMR | IG-DMR | Gtl2-DMR, 5′ | Gtl2-DMR, 3′ | |||
|---|---|---|---|---|---|---|---|---|
BxC | CxB | BxC | CxB | BxC | BxC | CxB | ||
% methylation (# methylated/total) | P | 42.5% (510/1199) | 42% (541/1287) | 96.1% (2960/3080) | 95.5% (2982/3123) | 79.5% (699/879) | 92.7% (306/330) | 85.9% (878/1034) |
M | 16.6% (251/1516) | 28.4% (367/1292) | 11.2% (110/918) | 12.2% (75/616) | 9.5% (64/671) | 6.2% (76/1231) | 6.4% (59/923) | |
total | 28% (761/2715) | 35.2% (908/2579) | 76.8% (3070/3998) | 81.8% (3057/3739) | 49.2% (763/1550) | 24.5% (382/1561) | 47.9% (937/1957) | |
% homomethylation (# homomethylated/total) | P | 79.5% (221/278) | 70.6% (223/316) | 94.2% (1436/1524) | 92.9% (1436/1545) | 76.3% (302/396) | 88.9% (144/162) | 82.5% (397/481) |
M | 63.4% (97/153) | 65.7% (140/213) | 39.7% (31/78) | 70.5% (31/44) | 12.2% (7/57) | 35.7% (20/56) | 31.1% (14/45) | |
total | 73.8% (318/431) | 68.6% (363/529) | 91.6% (1467/1602) | 92.3% (1467/1589) | 68.2% (309/453) | 75.2% (164/218) | 78.1% (411/526) | |
% hemimethylation (# hemimethylated/total) | P | 20.5% (57/278) | 29.4% (93/316) | 5.8% (88/1524) | 7.1% (109/1545) | 23.7% (94/396) | 11.1% (18/162) | 17.5% (84/481) |
M | 36.6% (56/153) | 34.3% (73/213) | 60.3% (47/78) | 29.5% (13/44) | 87.7% (60/57) | 64.3% (36/56) | 68.9% (31/45) | |
total | 26.2% (113/431) | 31.4% (166/529) | 8.4% (135/1602) | 7.7% (122/1589) | 31.8% (144/453) | 24.8% (54/218) | 21.9% (115/526) | |