Fig. 5

Ube3a is biallelically expressed in myenteric neurons of the PNS. a Immunofluorescence images of neurons in the myenteric ganglia of the peripheral nervous system of Ube3a ^m+/pYFP and Ube3a ^mYFP/p+ mice. b Immunofluorescence images of granular neurons in the dentate gyrus of Ube3a ^m+/pYFP and Ube3a ^mYFP/p+ mice. c Normalized intensity values of Ube3a^YFP protein levels in myenteric neurons of Ube3a ^m+/pYFP and Ube3a ^mYFP/p+ mice (n = 3 per genotype; Ube3a ^m+/pYFP: n = 22 neurons; Ube3a ^mYFP/p+: n = 28). Abbreviations TOPRO-3, nuclear stain; n.s., not significant. Individual data points provided with mean (gray bar chart) and 95% confidence intervals