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Fig. 5 | Epigenetics & Chromatin

Fig. 5

From: Differential DNA methylation and lymphocyte proportions in a Costa Rican high longevity region

Fig. 5

Pyrosequencing of significantly differentially methylated single CpGs. Left Bland–Altman plot of concordance between 450k array and pyrosequencing result for each CpG. Text labels represent sample IDs. Middle scatter plot displaying correlation between 450k array and pyrosequencing for each CpG. Spearman correlation coefficients shown. Right box plots of significant difference between Nicoyans and non-Nicoyans at each CpG site, measured using pyrosequencing. Significant value from regression model of CpG methylation on group status, while controlling for sex, age, and cell-type proportions

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