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Fig. 5 | Epigenetics & Chromatin

Fig. 5

From: Differential DNA methylation at conserved non-genic elements and evidence for transgenerational inheritance following developmental exposure to mono(2-ethylhexyl) phthalate and 5-azacytidine in zebrafish

Fig. 5

Ingenuity pathway analysis of mono(2-ethylhexyl) phthalate (MEHP) and 5-azacytidine (5AC)-specific differentially methylation regions (DMRs). Heat maps of −log(P) values for DMR-associated genes of a MEHP and b 5AC exposures. Heat maps show top 20 lists of predicted canonical pathways, upstream regulators, toxicology-related gene lists (Tox) of all (All), hypermethylated (hyper) and hypomethylated (hypo) DMRs, and DMR-specific zebrafish conserved non-genic elements (zfCNE). A custom imported list was also added (adipose tissue development). Extended lists are found in Additional file 3 and 4

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Epigenetics & Chromatin

ISSN: 1756-8935