Fig. 3

Gene expression analysis of dnmt variants and global methylation. a Log-normalized gene expression relative to control in F0 6 days post-fertilization larvae (Error bars represent SEM, *P < 0.05, ANOVA with Dunnets post hoc test). b Heat map of absolute differences in global cytosine methylation and cytosine hydroxymethylation compared to control. Black squares indicate significant changes relative to control (P < 0.05, two-tailed t test, using Bonferroni multiple comparisons correction). Gray indicates non-detectable levels