Fig. 6
From: Comprehensive evaluation of genome-wide 5-hydroxymethylcytosine profiling approaches in human DNA
hMeDIP-seq hydroxymethylation profiling in cell line DNA. a Scatter plot showing the correlation between hMeDIP-seq replicates in LNCaP cells. For each genomic tile from one replicate the average enrichment score for the second replicate was calculated. Each dot represents one genomic tile. b Scatter plot showing the correlation between hMeDIP-seq in LNCaP cells and public hMeDIP-seq in MCF7 cells. c Scatter plot showing the correlation between hMeDIP-seq in LNCaP cells and brain hMeDIP-seq. d Genomic region showing the correspondence of hMeDIP-seq replicates in LNCaP cells as well as MCF7 cells. e Density plot showing the distribution of p Bis − p OxBis values in the Brain versus LNCaP WG Bis/OxBis data. f The percentages of significantly hydroxymethylated CpGs of all CpGs with at least 10× coverage on the WG Bis/OxBis in the Brain versus LNCaP. g Density plot showing the distribution of p Bis − p OxBis values in the Brain versus LNCaP HM450K Bis/OxBis data. h The percentages of significantly hydroxymethylated CpGs of all CpGs with at least 10× coverage on the HM450K Bis/OxBis in the Brain versus LNCaP