Fig. 1

Binning analysis of nucleosome dyad co-alignment in the T. brucei genome. Binning analysis allows the visualization of nucleosome density and positioning in different genomic regions. The bin size (x axes) indicates the number of co-aligned nucleosome dyads reflecting nucleosome positioning strength, and the number of members in each bin (y axes) represents the number of times this degree of positioning was observed in the tested genomic region. a These analyses were performed on the entire T. brucei 427 genome using chromatin from either BF or PF. b Nucleosome distribution in the whole genome compared with AT-rich repeat sequences in BF chromatin. c Comparison of chromatin from BF and PF genomes excluding AT-rich repeat sequences. d Nucleosome distribution at the coding regions in BF and PF chromatin. e Comparison of nucleosome positioning at intergenic regions (SSRs as well as noncoding regions between individual genes in a PTU) in BF and PF T. brucei. f Nucleosomes at tRNA genes in BF and PF. g Nucleosomal distributions at the 5S subunit rRNA genes in BF and PF. The lines represent the best fit (least squares) line to the BF (black line) or PF (gray line) datasets, respectively