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Fig. 4 | Epigenetics & Chromatin

Fig. 4

From: Decoupling the downstream effects of germline nuclear RNAi reveals that H3K9me3 is dispensable for heritable RNAi and the maintenance of endogenous siRNA-mediated transcriptional silencing in Caenorhabditis elegans

Fig. 4

Global H3K9me3 contribution of MET-2, SET-25, and SET-32. a H3K9me3 levels are plotted as a function of position in chromosome V for WT and HMT mutant strains (the effect is the same for other chromosomes, see Additional file 3: Fig. S2). A moving average with a sliding window of 50 kb was used to plot H3K9me3 levels. b A Venn diagram of H3K9me3 regions that are dependent on SET-25, MET-2 SET-25, and MET-2 SET-25;SET-32. Targets were identified as regions with ∆H3K9me3[mutant/WT] ≤0.5 (FDR < 0.05) in two replica (Additional file 6: Fig. S3)

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