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Table 3 Manually curated list of human histones

From: MS_HistoneDB, a manually curated resource for proteomic analysis of human and mouse histones

Histone

Protein name

Entry name for MS analysis

Gene name

UniProtKB Accession

References

H1

H1.1

H1.1

Hist1h1a

Q02539

[41, 106, 107]

H1.2

H1.2

Hist1h1c

P16403

[41, 106, 107]

H1.3

H1.3

Hist1h1d

P16402

[41, 106, 107]

H1.4

H1.4

Hist1h1e

P10412

[41]

H1.5

H1.5

Hist1h1b

P16401

[41, 108]

H1.0 (H1°)

H1.0 (H1°)

H1f0

P07305

[109]

TS H1.6 (H1t)

TS H1.6 (H1t)

Hist1h1t

P22492

[41]

TS H1.7 (H1T2, HANP1)

TS H1.7 (H1T2, HANP1)

H1fnt

Q75WM6

[110]

OO H1.8 (H1oo)

OO H1.8.s1 (H1oo)

H1foo

Q8IZA3-1

[111, 112]

OO H1.8.s2 (putative spliced isoform)

H1foo

Q8IZA3-2

*

TS H1.9 (Hils)

TS H1.9 (Hils)

Hils1

P60008

[57]

H1.10

H1.10

H1fx

Q92522

[113]

H2A

Canonical H2A

Canonical H2A genes: Hist1h2ag, Hist1h2ai, Hist1h2ak, Hist1h2al, Hist1h2am

Hist1h2ag

P0C0S8

[41]

Hist1h2ai

P0C0S8

[41]

Hist1h2ak

P0C0S8

[41]

Hist1h2al

P0C0S8

[41]

Hist1h2am

P0C0S8

[41]

Canonical H2A gene: Hist1h2ac

Hist1h2ac

Q93077

[41]

Canonical H2A gene: Hist1h2ad

Hist1h2ad

P20671

[41]

Canonical H2A gene: Hist1h2ae

Hist1h2ae

P04908

[41]

Canonical H2A gene: Hist1h2ah

Hist1h2ah

Q96KK5

[41]

Canonical H2A gene: Hist1h2aj

Hist1h2aj

Q99878

[41]

Canonical H2A gene:Hist2h2aa4

Hist1h2aa4

Q6FI13

[41]

Canonical H2A gene: Hist2h2ab

Hist2h2ab

Q8IUE6

[41]

Canonical H2A gene: Hist2h2ac

Hist2h2ac

Q16777

[41]

Canonical H2A gene: Hist3h2a

Hist3h2a

Q7L7L0

[41]

Canonical H2A (pseudogene)

Hist1h2Aps4

Q92646

***

H2A.J (putative variant)

H2A.J.s1

H2afj

Q9BTM1-1

**

H2A.J.s2 (putative spliced isoform)

H2afj

Q9BTM1-2

**

H2A.J.s3 (putative spliced isoform)

H2afj

H0YFX9

Short**

H2A.X

H2A.X

H2afx

P16104

[61, 114]

H2A.Z.1

H2A.Z.1

H2afz

P0C0S5

[115, 116]

H2A.Z.2

H2A.Z.2.s1

H2afv

Q71UI9-1

[116]

H2A.Z.2.s2

H2afv

Q71UI9-2

[65]

H2A.Z.2.s3 (putative spliced isoform)

H2afv

Q71UI9-4

[65]

H2A.Z.2.s4 (putative spliced isoform)

H2afv

Q71UI9-5

[65]

H2A.Z.2.s5 (putative spliced isoform)

H2afv

Q71UI9-3

[65]

H2A.Z.2.s6 (putative spliced isoform)

H2afv

C9J0D1

*

H2A.Z.2.s7 (putative spliced isoform)

H2afv

C9J386

Short*

H2A.Z.2.s8 (putative spliced isoform)

H2afv

E5RJU1

Short*

macroH2A.1

macroH2A.1.s1

H2afy

O75367

[117]

macroH2A.1.s2

H2afy

O75367-2

[66]

macroH2A.1.s3 (putative spliced isoform)

H2afy

B4DJC3

*

macroH2A.1.s4 (putative spliced isoform)

H2afy

D6RCF2

***

macroH2A.1.s5 (putative spliced isoform)

H2afy

O75367-3

*

macroH2A.2

macroH2A.2.s1

H2afy2

Q9P0M6

[96, 97]

macroH2A.2.s2 (putative spliced isoform)

H2afy2

Q5SQT3

*

TS H2A.1 (TH2A)

TS H2A.1 (TH2A)

Hist1h2aa

Q96QV6

[71]

H2A.B.1

H2A.B.1

H2afb1

P0C5Y9

[118, 119]

H2A.B.2

H2A.B.2

H2afb2

P0C5Z0

*

H2afb3

H2A.P

H2A.P

Hypm

O75409

*

H2B

Canonical H2B

Canonical H2B gene: Hist1h2bb

Hist1h2bb

P33778

[41]

Canonical H2B genes: Hist1h2bc, Hist1h2be, Hist1h2bf, Hist1h2bg, Hist1h2bi

Hist1h2bc

P62807

[41]

Hist1h2be

P62807

[41]

Hist1h2bf

P62807

[41]

Hist1h2bg

P62807

[41]

Hist1h2bi

P62807

[41]

Canonical H2B gene: Hist1h2bd

Hist1h2bd

P58876

[41]

Canonical H2B gene: Hist1h2bh

Hist1h2bh

Q93079

[41]

Canonical H2B gene: Hist1h2bj

Hist1h2bj

P06899

[41]

Canonical H2B gene: Hist1h2bj (putative spliced isoform)

Hist1h2bj

U3KPT8

*

Canonical H2B gene: Hist1h2bk

Hist1h2bk

O60814

[41]

Canonical H2B gene: Hist1h2bl

Hist1h2bl

Q99880

[41]

Canonical H2B gene: Hist1h2bm

Hist1h2bm

Q99879

[41]

Canonical H2B gene: Hist1h2bn

Hist1h2bn

Q99877

[41]

Canonical H2B gene: Hist1h2bn (putative spliced isoform)

Hist1h2bn

U3KQK0

[41]

Canonical H2B gene: Hist1h2bo

Hist1h2bo

P23527

[41]

Canonical H2B gene: Hist2h2be

Hist2h2be

Q16778

[41]

Canonical H2B gene: Hist2h2bf (putative spliced isoform)

Hist2h2bf

Q5QNW6

*

Canonical H2B gene: Hist2h2bf (putative spliced isoform)

Hist2h2bf

Q5QNW6-2

*

Canonical H2B gene: Hist3h2bb

Hist3h2bb

Q8N257

[41]

H2B.S (putative variant)

H2B.S (putative variant)

H2bfs

P57053

*

H2B.M (putative variant)

H2B.M.s1 (putative variant)

H2bfm

P0C1H6

*

H2B.M.s2 (putative variant, putative spliced isoform)

H2bfm

A9UJN3

Short*

H2B.W

H2B.W

H2bfwt

Q7Z2G1

[72, 120, 121]

TS H2B.1 (TH2B)

TS H2B.1 (TH2B)

Hist1h2ba

Q96A08

[41, 71]

H3

Canonical H3.1

Canonical H3.1 genes: Hist1h3a, Hist1h3b, Hist1h3c, Hist1h3d, Hist1h3e, Hist1h3f, Hist1h3g, Hist1h3h, Hist1h3i, Hist1h3j

Hist1h3a

P68431

[41]

Hist1h3b

P68431

[41]

Hist1h3c

P68431

[41]

Hist1h3d

P68431

[41]

Hist1h3e

P68431

[41]

Hist1h3f

P68431

[41]

Hist1h3g

P68431

[41]

Hist1h3h

P68431

[41]

Hist1h3i

P68431

[41]

Hist1h3j

P68431

[41]

Canonical H3.2

Canonical H3.2 genes: Hist2h3a, Hist2h3c, Hist2h3d

Hist2h3a

Q71DI3

[41]

Hist2h3c

Q71DI3

[41]

Hist2h3d

Q71DI3

[41]

Canonical H3.2 (pseudogene)

Hist2h3ps2

Q5TEC6

*

H3.3

H3.3.s1

H3f3a

P84243

[122, 123]

H3f3b

P84243

[122, 123]

H3.3.s2 (putative spliced isoform)

H3f3a

B4DEB1

*

H3f3b

B4DEB1

*

H3.3.s3 (putative spliced isoform)

H3f3b

K7EK07

*

H3.3.s4 (putative spliced isoform)

H3f3b

K7EMV3

*

H3.3.s5 (putative spliced isoform)

H3f3b

K7EP01

*

H3.3.s6 (putative spliced isoform)

H3f3b

K7ES00

*

H3.Y.1

H3.Y.1

H3.Y

Translated from NG_012784.2

[44]

H3.Y.2 (H3.X)

H3.Y.2 (H3.X)

H3.X

Translated from NG_023411.2

[44]

H3.5

H3.5

H3f3c

Q6NXT2

[75]

cenH3-CENPA

cenH3 - CENPA

Cenpa

P49450-1

[124]

cenH3.s1 (putative spliced isoform)

Cenpa

P49450-2

*

cenH3.s2 (putative spliced isoform)

Cenpa

F8WD88

Short**

TS H3.4 (H3t)

TS H3.4 (H3t)

Hist3h3

Q16695

[41]

H4

H4

H4

Hist1h4a

P62805

[41]

Hist1h4b

P62805

[41]

Hist1h4c

P62805

[41]

Hist1h4d

P62805

[41]

Hist1h4e

P62805

[41]

Hist1h4f

P62805

[41]

Hist1h4h

P62805

[41]

Hist1h4i

P62805

[41]

Hist1h4j

P62805

[41]

Hist1h4k

P62805

[41]

Hist1h4l

P62805

[41]

Hist2h4a

P62805

[41]

Hist2h4b

P62805

[41]

Hist4h4

P62805

[41]

  1. Please refer to the Table 2 for legend. The corresponding FASTA file is presented as Additional file 2. Additional file 5 presents links to gene, transcripts and protein entries to Ensembl and UniProtKB databases