Fig. 1
From: “Gap hunting” to characterize clustered probe signals in Illumina methylation array data
An example of a gap signal detected in SEED at cg01802772 via gap hunting. Top panel Gap hunting-identified groups are shown in black, red, and green and correspond to measured SEED genotypes TT, TC, and CC, respectively, at rs299872. Bottom panel Depiction of variant locations relative to probe orientation. Blue color denotes the single-base extension site which also corresponds to the interrogated CpG site for this probe type (Type II); black color denotes 50 bp probe length. Y-axis lists variants present in the dbSNP138 database with a frequency greater than 0.5% and validated in more than 200 people