Fig. 2

a Saturation curve showing the number of bases called as being in peaks as a function of sequencing depth. The final dataset of the merged technical replicates was randomly downsampled to 20 different read depths, and peaks were called in each dataset using HOMER. b Distribution of the canonical ENCODE regions of the genomic bases identified as being in peaks. Note that distribution of bases called in both the monoclonal and polyclonal antibody differs from the distribution of bases called by only one antibody with fewer bases in their expected regions. c Left bases of the genome that were designated as peaks were identified as being in the expected canonical ENCODE region versus other regions. Only genomic bases annotated in the ENCODE segmentation tracks for K562 are included in this calculation. Right Venn diagrams displaying the overlap of peak calls in the monoclonal and polyclonal antibodies. The bases of the genome are identified as being in peaks by the monoclonal (red), polyclonal (blue) or both (purple) antibodies