Fig. 5

Lens-specific and common Pax6 peaks of mouse lens chromatins show similar histone modification patterns. a Lens-specific Pax6 peaks are co-localized with H3K4me1, and H3K4me2 in mouse lens tissue. Heatmap shows read density in 50-bp bins from −5 to +5 kb of the peak summits at lens-specific Pax6 peaks (n = 3478). b Common Pax6 peaks are co-localized with H3K4me1, and H3K4me2 in both lens tissue and αTN4 cells. Heatmap shows read density in 50-bp bins from −5 to +5 kb of the peak summits at Pax6 common peaks between lens tissue and αTN4 cells (n = 245). c αTN4 specific Pax6 peaks are co-localized with H3K4me1, and H3K4me2 in αTN4 cells. The right panel shows mean ChIP-seq read density for all ChIP-seq data from −5 to +5 kb around Pax6 peak summits