Fig. 4

Pax6-binding site analysis and identification of enriched motifs around Pax6 peak summits. a 502 Pax6 peaks were identified in αTN4 chromatin, including 245 shared with the newborn mouse lens chromatin. b 502 Pax6 peaks identified in αTN4 chromatin are enriched with Pax6 motifs similar to those identified from 3723 Pax6 peaks in lens chromatin and by in vitro DNA-binding studies. c Additional motifs assigned to Ets, Meis, and AP-1 families of transcription factors were also identified at the Pax6 peaks. The regions examined are defined as ±100 bp under the Pax6 peak summits