Fig. 3

Lens Pax6 promoter and non promoter peaks show different histone modification patterns in mouse lens chromatin. a Pax6 promoter peaks are co-localized with H3K4me2, H3K4me3 and H3K27ac in mouse lens chromatin. b Lens Pax6 non-promoter peaks are co-localized with H3K4me1, H3K4me2, and H3K27ac. The heatmap shows read densities in 50-bp bins from ±5 kb of the Pax6 peak summits. Pax6, RNA polymerase II, H3K4me1, H3K4me2, H3K4me3, H3K27ac, H3K27me3 ChIP-seq data in lens tissue are shown. The lower panels show mean ChIP-seq read densities from −5 to +5 kb around Pax6 peak summits. The rows in the heatmaps were sorted by the Pax6 signals (likewise in Figs. 5, 7).