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Table 1 Lists of overrepresented transcription factor binding motifs in differentially methylated regions using the Transfac database and default settings for the experimental and the random data set

From: Epigenetic dynamics of monocyte-to-macrophage differentiation

Factor Versus experimental set (A) Versus random set (B)
Yes No Yes/no Yes No Yes/no
AP-1 0.1667 0.0038 43.6333 0.1667 0.0175 9.5000
RelA-p65 0.1404 0.0130 10.8070 0.1140 0.0175 6.5000
MAF 0.1754 0.0260 6.7544 0.1140 0.0088 13.0000
Muscle initiator 0.1228 0.0191 6.4302 0.1667 0.0439 3.8000
GEN_INI 0.4474 0.0718 6.2298 0.1053 0.0088 12.0000
GKLF 0.6140 0.1406 4.3683 0.6140 0.0877 7.0000
Myogenin 0.9474 0.2231 4.2469 0.9474 0.2632 3.6000
CPBP 2.0877 0.6157 3.3906 2.0877 1.0877 1.9194
BBX secondary motif 0.0439 0.0023 19.1374    
RFX1 0.0526 0.0038 13.7789    
TTF-1 0.1404 0.0237 5.9264    
AHR 0.2281 0.0413 5.5286    
ZNF333 0.8772 0.5225 1.6787    
Ikaros     0.5965 0.0263 22.6667
SREBP     0.1404 0.0088 16.0000
Ets     0.1140 0.0088 13.0000
Helios A     0.1140 0.0088 13.0000
MZF-1     0.2193 0.0526 4.1667
Smad4     0.1842 0.0526 3.5000
NF-AT1     0.5351 0.1754 3.0500
MAFA     0.2105 0.0702 3.0000
FAC1     0.2456 0.0877 2.8000
ING4     0.6316 0.2368 2.6667
SRY     0.6579 0.2895 2.2727
  1. Yes and No denote the relative number of sites for the selected matrix in the DMRs as compared to an experimental data set (A) and a random data set (B)