Table 1 Lists of overrepresented transcription factor binding motifs in differentially methylated regions using the Transfac database and default settings for the experimental and the random data set
From: Epigenetic dynamics of monocyte-to-macrophage differentiation
Factor | Versus experimental set (A) | Versus random set (B) | ||||
|---|---|---|---|---|---|---|
Yes | No | Yes/no | Yes | No | Yes/no | |
AP-1 | 0.1667 | 0.0038 | 43.6333 | 0.1667 | 0.0175 | 9.5000 |
RelA-p65 | 0.1404 | 0.0130 | 10.8070 | 0.1140 | 0.0175 | 6.5000 |
MAF | 0.1754 | 0.0260 | 6.7544 | 0.1140 | 0.0088 | 13.0000 |
Muscle initiator | 0.1228 | 0.0191 | 6.4302 | 0.1667 | 0.0439 | 3.8000 |
GEN_INI | 0.4474 | 0.0718 | 6.2298 | 0.1053 | 0.0088 | 12.0000 |
GKLF | 0.6140 | 0.1406 | 4.3683 | 0.6140 | 0.0877 | 7.0000 |
Myogenin | 0.9474 | 0.2231 | 4.2469 | 0.9474 | 0.2632 | 3.6000 |
CPBP | 2.0877 | 0.6157 | 3.3906 | 2.0877 | 1.0877 | 1.9194 |
BBX secondary motif | 0.0439 | 0.0023 | 19.1374 | |||
RFX1 | 0.0526 | 0.0038 | 13.7789 | |||
TTF-1 | 0.1404 | 0.0237 | 5.9264 | |||
AHR | 0.2281 | 0.0413 | 5.5286 | |||
ZNF333 | 0.8772 | 0.5225 | 1.6787 | |||
Ikaros | 0.5965 | 0.0263 | 22.6667 | |||
SREBP | 0.1404 | 0.0088 | 16.0000 | |||
Ets | 0.1140 | 0.0088 | 13.0000 | |||
Helios A | 0.1140 | 0.0088 | 13.0000 | |||
MZF-1 | 0.2193 | 0.0526 | 4.1667 | |||
Smad4 | 0.1842 | 0.0526 | 3.5000 | |||
NF-AT1 | 0.5351 | 0.1754 | 3.0500 | |||
MAFA | 0.2105 | 0.0702 | 3.0000 | |||
FAC1 | 0.2456 | 0.0877 | 2.8000 | |||
ING4 | 0.6316 | 0.2368 | 2.6667 | |||
SRY | 0.6579 | 0.2895 | 2.2727 | |||