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Fig. 6 | Epigenetics & Chromatin

Fig. 6

From: Chromatin variation associated with liver metabolism is mediated by transposable elements

Fig. 6

Variable TEs are associated with diet-induced gene expression changes. a Fold change (HF/HS over control) of C57BL/6J FAIRE-seq reads at variable TE sites, common TE sites or random accessible sites. Box plots show the median value, and whiskers show distribution of first and third quartile (**indicates p < 0.0001, Wilcoxon's rank-sum test). b Enriched biological processes of accessible LINEs specific for HF/HS-fed C57BL/6J mice (4339 regions). Genomic coordinates were used as input for GREAT analysis. c, d Genome browser views of LINE-associated diet-induced chromatin remodeled sites nearby diet-induced metabolic genes, Dusp1 (b) and Herpud1 (c). Numbers in parentheses for RNA-seq tracks represent FPKM values

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