Fig. 4
From: DNA methylation signature of human fetal alcohol spectrum disorder
Several CpGs associated with SLC22A18 displayed down-methylation in FASD cases. The covariate-adjusted DNA methylation levels for control (gray) and FASD (blue) samples are shown for SLC22A18AS (top), with the gene structure aligned (bottom). Exons are represented by blocks, and transcriptional direction is indicated by arrows. All CpG sites are noted, those present on the 450K array are black while CpGs not present are gray. The six significantly differentially methylated probes located in the SLC22A18 promoter region are indicated with the horizontal black bar [FDR-adjusted p-value (q) <0.05]