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Fig. 3 | Epigenetics & Chromatin

Fig. 3

From: DNA methylation signature of human fetal alcohol spectrum disorder

Fig. 3

Differentially methylated probes are located in regions of variable and intermediate DNA methylation. a The 658 probes differentially methylated between FASD and control were underrepresented in CGI cores (down-methylated p = 1.62E−6; up-methylated p = 7.53E−4), while down-methylated probes were overrepresented in CGI shores/shelves (p = 0.04; p = 0.0003) and up-methylated probes were overrepresented in non-CpG island regions (p = 0.009). b The same probes’ average methylation levels are overrepresented in the mid-range categories (**p < 0.01, ***p < 0.0001)

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