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Table 3 Top ten MeCP2-enriched promoters and genes identified by ChIP-seq in the DRG from SNI model compared to sham control

From: Genome-wide redistribution of MeCP2 in dorsal root ganglia after peripheral nerve injury

Nearest refseq

Gene name

Gene description

Tag count

p value

Sham

SNI

Promoters with enriched MeCP2 binding

 NM_021478

Tulp1

Tubby like protein 1

0

30

2.85E−06

 NM_027398

Kcnip1

Kv channel-interacting protein 1

0

19

0.000195

 NM_170757

Ccdc186

Coiled-coil domain containing 186

0

16

0.000629

 NM_001034898

Ms4a15

Membrane-spanning 4-domains, subfamily A, member 15

0

25

1.92E−05

 NR_033168

Snora28

Small nucleolar RNA, H/ACA box 28

0

26

1.31E−05

 NM_001113379

Lrrc32

Leucine rich repeat containing 32

0

25

1.92E−05

 NM_011305

Rxra

Retinoid X receptor alpha

0

15

0.000932

 NM_018820

Sertad1

SERTA domain containing 1

0

17

0.000425

 NM_001011525

Olfr1415

Olfactory receptor 1415

0

16

0.000629

 NM_133759

Zbtb3

Zinc finger and BTB domain containing 3

0

25

1.92E−05

Gene bodies with enriched MeCP2 binding

 NM_001001807

Olfr279

Olfactory receptor 279

0

21

8.97E−05

 NM_011540

Tcap

Titin-cap

0

16

0.000629

 NM_011971

Psmb3

Proteasome (prosome, macropain) subunit, beta type 3

0

19

0.000195

 NM_198414

Paqr9

Progestin and adipoQ receptor family member IX

0

20

0.000132

 NM_133668

Slc25a3

Solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3

0

15

0.000932

 NM_001160356

Uqcc3

Ubiquinol-cytochrome c reductase complex assembly factor 3

0

15

0.000932

 NM_001190356

Gm4832

Predicted gene 4832

0

15

0.000932

 NM_133759

Zbtb3

Zinc finger and BTB domain containing 3

0

25

1.92E−05

 NM_009296

Supt4a

Suppressor of Ty 4A

0

20

0.000132

 NM_009756

Bmp10

Bone morphogenetic protein 10

0

18

0.000288