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Table 1 Histone isoforms and post-translational modifications (PTMs) identified during mouse spermatogenesis and in mature mouse sperm

From: Comprehensive analysis of histone post-translational modifications in mouse and human male germ cells

Histone isoforms
H1 H1.0, H1.1, H1.2, H1.4, H1.5, H1.t, HILS
H2A H2A.1, H2A.1h, H2A.2a, H2A.2b, H2A.2c, H2A.3, H2A.J, H2A.V, H2A.X, H2A.Z
H2B tH2B, H2B.1b, H2B.1h, H2B.1k, H2B.1m, H2B.1p, H2B.2b, H2B.2e, H2B.3a, H2B.3b
H3 H3, H3.1, H3.3
H4 H4
Histone post-translational modifications
 M  
  H1 K16ac, K21me1, S57ph, K63me
  H1t M58ox, S59ph, K64me2, K65me3, K76ac, R80me1, S140ph, K142ac, K145me1/3, T146ph, K147cr, K150ac, K151me1, K170ac, S177ph, K190me1, K192cr, M193ox, M195ox
  H2A K5ac, K9ac, R35me1, K36ac, K74ac, R77me1, K125ac, K129me1
  H2AV/Z K11cr, K11me2, K13cr, K13me2/3, K15ac, K15me3, S18ph, R19me1
  H2B S4phb, K5ac, K5me1/2/3, S6ph, K11ac, K11cr, K11me1/2/3, K12ac, K12cr, K12me1/3, S14ph, K15ac, K15cr, K15me1/3, K16ac, K16cr, K16me1/3, K20ac, K24me3, K27me1, K27cr, K28me3, R29me1, K120me2, S123ph, K125me3
  tH2B K6ac, K6cr, K6me1/3, K12ac, K12me1/3, K13cr, K13me1, K16ac, K16cr, K16me1/3, K17cr, K21ac, K24ac, K25me1
  H3 K4me1, K9me1/2/3, K14ac, K23me1/2, R26me, K27me1/2/3, K36ac, K36me1/2/3, K37me3, R53me1, K56ac, K79me1/2, M120ox
  H4 K5ac, K8ac, K12ac, K12me1, K12cr, K16ac, K16cr, R17me1, K20me1/2/3, K31ac, R35me1, M84ox, K91ac, R92me1
 RS
  H1 K16ac, S40ph, S57ph, K63me1
  H1t M58ox, S59ph, K64me1/3, K76ac, R80me1, S140ph, K142ac, S144ph, K145me2/3, T146ph, K147ac, K147cr, K147me1, K150ac, K170ac, S177ph, M193ox, M195ox
  H2A K5ac, R35me1, K36ac, K125ac, K129me1
  H2Z K4ac, K11cr, K11me2, K13cr, K13me2, T14ph, K15me3, K15ac, R19me1
  H2B S4ph b, K5ac, K5cr, K5me1/2/3, R5me a, K11ac, K11me1/3, K12ac, K12cr, K12me1/2/3, S14ph, K15ac, K15cr, K15me1/2/3, K16ac, K16cr, K16me1/3, K20ac, K24me3, K27cr, K28ac, K28cr, R29me1, K120me2, S123ph, K125me3
  tH2B K6ac, K6me1, S11ph, K12me,1 K13ac, K13me1/3, K16ac, K16me1, K16cr, K17me1, K21ac
  H3 K4me1, K9me1/2/3, K14ac, K18me1/2, K23me1/2, R26me1, K27me1/2/3, K36me1/2/3, R53me1, K56ac, K79me1/2, M120ox
  H4 K5ac, K8ac, K12ac, K12me1, K16ac, K16me1, R17me1, K20me1/2/3, K31ac, R35me1, M84ox, K91ac, R92me1
 ES
  H1 K16ac, S57ph, K63me1, K74ac, R78me1
  H1t M58ox, K76ac, R80me1, S140ph, K142ac, T146ph, K147me1, K147cr, K151me3, K170ac, M193ox, M195ox
  H2A K5ac, K74ac, K75ac, R77me1
  H2AZ K11me2, K13me2, T14ph, K15ac, K15me3, R19me1
  H2B K5ac, K5cr, K5me1, K11ac, K11me1/2, K12me1/3, K15cr, K15me1, K16ac, K16cr, K16me1, K120me2, S123ph, K125me3
  tH2B K6ac, K12me3, K13me1, K16me1, K17me1, K21ac
  H3 K9me1/2/3, K14ac, K23ac, K23me1, R26me1, K27me1/2/3, K36ac, K36me1/2, K37me3, R53me1, K56ac, K79me1/2, M120ox
  H4 K5ac, K8ac, K12ac, K16ac, K20me1/2/3, M84ox, K91ac, R92me1
 Sp  
  H1 K19ac c, K25me1, K27me1 c, M30ox c
  H2A M51ox, K74ac, K75ac, R77me1
  H2AV/Z K7ac, K11cr, K11me2, K13cr, K13me1/2, T14ph, K15cr, K15me1/3, S18ph, K74me3, K77cr, K79cr
  H2B K5ac, K5cr, K5me1/2, S6ph, K11ac, K11me1/3, K12ac, K12cr, K12me1/3, S14ph, K15ac, K15cr, K15me1/3, K16ac, K16cr, K16me1, K24me3, K27cr, K27me1, K28ac, K28cr, K28me3, R29me1, K120me2, S123ph, K125me3
  H3 K9me1/2/3, K14ac, K23ac, R26me1, K27me1/2/3, K36ac, K36me1/2, K37me3, K37cr, R40me1, R53me1, K56ac, K79me1/2, M120ox
  H4 K5ac, K8ac, K12ac, K16ac, R17me1, K20me1/2/3, M84ox, K91ac, K91cr, R92me1
  1. Includes PTMs identified on any isoform except those with modified, non-conserved amino acid residues (H1t, H2AV, H2AZ, tH2B). Underlined PTMs do not appear in the subsequent cell stage, and italicized PTMs were not present in the previous cell stage
  2. aR5 is present only on the H2B3A isoform
  3. bS4 is present only on H2B3B isoform
  4. cPresent only on H1.0 isoform