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Fig. 6 | Epigenetics & Chromatin

Fig. 6

From: Abnormal X chromosome inactivation and sex-specific gene dysregulation after ablation of FBXL10

Fig. 6

a Underexpression in Fbxl10 T/T female embryos of selected genes that encode factors reported to interact with Xist RNA [14]. b Expression of genes that encode Xist RNA-binding factors in female Fbxl10 T/T embryos (bottom); normal expression of the same genes in male Fbxl10 T/T embryos (top). Analysis was performed via GSEA [13]. These data indicate that the overexpression of Xist RNA as shown in Fig. 5 is concomitant with reduced levels of proteins that associate with Xist RNA

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