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Fig. 3 | Epigenetics & Chromatin

Fig. 3

From: Abnormal X chromosome inactivation and sex-specific gene dysregulation after ablation of FBXL10

Fig. 3

Sex-specific gene dysregulation in Fbxl10 T/T embryos. a Representative littermate embryos dissected at embryonic day 9.5. Males and females are indistinguishable on the basis of their morphology at this stage of development. b Greater variation in gene expression in female mutant embryos as determined by RNA-seq. c Examples of sex-specific expression abnormalities in Fbxl10 T/T embryos. The Ddit4, Vegfa, and Stc2 genes, and the imprinted gene Meg3, are all markedly overexpressed in female Fbxl10 T/T embryos

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