Fig. 3

Variable DNA methylation at ERVs. a Heatmap representing the 55 iiDMRs overlapping ERV elements. For these sites, the weighted average CpG methylation for each mouse is shown. Unsupervised clustering was performed. Data for the yellow mouse are shown but were not used to identify the differentially methylated sites. b The range of methylation at each ERV iiDMR (n = 55) for the five mice is shown and compared with that of all 301 iiDMRs generated from Additional file 1: Table S3 after removal of the ERV-associated loci. ERV iiDMRs have a significantly greater range (T test, p value <0.05)