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Fig. 5 | Epigenetics & Chromatin

Fig. 5

From: Functionally distinct patterns of nucleosome remodeling at enhancers in glucocorticoid-treated acute lymphoblastic leukemia

Fig. 5

Four modes of remodeling describe distinct subsets of GR peaks and enhancers. a Box and whisker plot of relative GR peak size reveals significant differences in GR peak size associated with each mode of remodeling. For all box and whisker plots, hinges of box are at located at 1st and 3rd quartiles. Whiskers extend to 1.5x interquartile range (IQR). Dots represent outlier observations. Notches signify an estimated 95 % confidence interval around the median. P-values estimated by Kolmogorov–Smirnov test using all GR peaks as reference distribution. b Frequency of GRE sequence motifs among different modes of remodeling. Modes differ significantly in their pre-existing enhancer strength, as measured by degree of H3K27Ac (c) and proportion of DHS (d). p-values for (b, d) calculated by Fisher’s exact test

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