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Fig. 4 | Epigenetics & Chromatin

Fig. 4

From: A rapid passage through a two-active-X-chromosome state accompanies the switch of imprinted X-inactivation patterns in mouse trophoblast stem cells

Fig. 4

Global reactivation of the paternal X precedes the switching of X-inactivation profiles in female TS cells. Histograms showing the paternal and maternal expression levels of Xist and X-linked genes Cox7b and Pgk1 in the indicated HAT-resistant clone assessed by allelic RT-qPCR. Two different time points during the selection procedure have been analysed: clones at passage 2 (pass.2) after clone picking (still under HAT selection) and the same clones after 6 additional passages without HAT (pass.8). Above the histograms, the diagram depicts the scheme of the HAT selection experiment used to isolate HAT-resistant clones analysed in this panel. Standardisation by Rplp0 has been applied. A.U. Arbitrary Units

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Epigenetics & Chromatin

ISSN: 1756-8935