Fig. 3

Class II CBP regions have low DNase hypersensitivity and become active late in development. a DNase hypersensitivity within 150 bp of the CBP peak in the nine classes of CBP regions. b GAGA, c GATAe and d GTGT motifs identified from CBP Class II regions. e Developmental expression of genes proximal to Class II CBP peaks. For each gene the relative change in expression from the previous time point was used. Values were linearly adjusted so that the global mean was zero. The embryo time points range from 0–24 h (in 2 h intervals) and the larval stages are as follows: larva L1, L2, L3 (12 h), L3 (puff stage 1–2), L3 (puff stage 3–6), L3 (puff stage 7–9). The pupae stages are: white pupae new, 12 h, 24 h, and 2, 3 and 4 days post white pupae. The adult time points are as follows: males 1 day, males at 5 days, males at 30 days, females at 1 day, females at 5 days and females at 30 days. f H3K23ac enrichment within 500 bp around CBP peak centres in the nine classes of CBP regions. Values were scaled so that a value of zero corresponds to the genomic mean and a value of one to the genomic maximum in a and f. Error bars represent 95 % confidence intervals