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Fig. 7 | Epigenetics & Chromatin

Fig. 7

From: RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships

Fig. 7

Chromatin organizational studies at RNA:DNA hybrids using mass spectrometry. In panel a we show the experimental approach used for these proteomic studies. In b the altered pattern of enriched proteins compared with the input sample is seen using gel electrophoresis, and the results of Western blots confirming the enrichment of specific candidate proteins identified by mass spectrometry (ILF2, ILF3, hnRNP C1/C2), with SP1 and SP3 as controls known to bind to G-skewed DNA motifs

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