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Fig. 4 | Epigenetics & Chromatin

Fig. 4

From: Tip60 complex binds to active Pol II promoters and a subset of enhancers and co-regulates the c-Myc network in mouse embryonic stem cells

Fig. 4

Tip60 is a positive transcriptional co-activator. a All the identified Tip60 peaks (100 %) were annotated to different genomic elements: Promoter-TSS, UTRs (untranslated regions), exons, introns, TSS and intergenic regions and are represented in the % of their presence at these elements. b Boxplots showing the log2 of RNA fragments per kilobase per million mapped fragments (FPKM) expression values from ESCs (GSE34473) of all analysed genes and Tip60 bound genes. cd RNA expression values are ranked into five groups with equal number of genes from highest to lowest RNA expression level as indicated. Boxplots represent the Pol II densities (c) or the Tip60 peak density (d) around the TSSs. Only density values higher than zero were taken. The median is significantly different between groups, if the notches do not overlap

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