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Fig. 3 | Epigenetics & Chromatin

Fig. 3

From: Tip60 complex binds to active Pol II promoters and a subset of enhancers and co-regulates the c-Myc network in mouse embryonic stem cells

Fig. 3

Tip60 and c-Myc binding overlap. a–b Heatmap representing k-means clustering results of normalized Tip60 (GSE69671), Pol II (GSM307623), c-Myc (GSM288356), Oct4 (GSM288347), Sox2 (GSM288346) and Nanog (GSM288345) density profiles against all 7693 MACS14 Tip60 peaks (a), or against all 5318 MACS14 c-Myc peaks (b). Two main clusters are observed. Cluster 1 shows Tip60 and c-Myc overlap in both panels. The colour scale bars under each data set in a and b reflect the read densities between 1 and 25 of the given dataset. The number of reads of each data set is indicted in the colour scale bars in millions (m) of reads

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Epigenetics & Chromatin

ISSN: 1756-8935