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Fig. 2 | Epigenetics & Chromatin

Fig. 2

From: Remodeling of nuclear landscapes during human myelopoietic cell differentiation maintains co-aligned active and inactive nuclear compartments

Fig. 2

IC channels and nuclear pores. a upper and mid panel: In all studied cell types IC channels penetrate peripheral (hetero)chromatin toward the nuclear envelope (arrows) as shown in vertical (yz) sections of 3D-SIM acquisitions. Bottom panel xy mid-sections from the respective nuclei for comparison. b surface rendering of 3D reconstructions (Amira) of the same nuclei shown in (a) reveal small “chromatin holes” mirroring exit point of IC channels (nuclear pores, [23, 24]) at the nuclear envelope. Scale bars 2 µm, insets 0.5 µm

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Epigenetics & Chromatin

ISSN: 1756-8935