Fig. 4
From: The histone chaperone DAXX maintains the structural organization of heterochromatin domains
DAXX maintains the structural integrity of nucleoli and the organization of rDNA. a B23-labeled IF images. Arrowheads indicate the mini nucleoli. Arrows indicate the line scan intensity plot and direction. Scale bar 5 µm. b Quantification of the percentage of cells containing a minimum of one mini nucleolus. Error bars represent SEM of a minimum of 100 cells. c FISH of rDNA (red) and IF microscopy of B23 (green). Arrowheads indicate rDNA foci found outside of the B23-defined nucleolar boundaries. Scale bar, 5 µm. d Box plot of the fraction of rDNA foci found outside of the nucleolar boundaries