Table 2 Characterization of histone H3 variants incorporated into chromatin
From: Tissue-specific expression of histone H3 variants diversified after species separation
H3 variant | AA alternation (from) | Motif 87–90 | Edit distance [nt] (from) | mRNA/protein | Chromatin incorporable | Tissue specificity | Expression pattern | Distribution pattern |
|---|---|---|---|---|---|---|---|---|
H3.1 | S96C (H3.2) | SAVM | – | – | Yes | – | D1/2 | Global |
H3t | A24V, R42H, A98S (H3.1) | SAVM | 52 (Hist1h3a) | Protein | Yes | Testis | D1/2 | Global |
H3.2 | C96S (H3.1) | SAVM | 10 (Hist1h3a) | – | Yes | – | D1/2 | Global |
H3.3 | A31S, S87A, V89I, M90G (H3.2) | AAIG | – | – | Yes | – | D3 | Local |
H3mm6 | #11 (H3.3) | AAIG | 15 (H3f3a) | None | No | – | – | – |
H3mm7 | T32I, S57A (H3.3) | AAIG | 3 (H3f3a) | Protein | Yes | SKMa, testis | D3 | Local |
H3mm8 | #23 (H3.3) | AAIG | 68 (H3f3b) | mRNA | No | – | – | – |
H3mm9 | #51 (H3.3) | AAIG | 102 (H3f3a) | None | No | – | – | – |
H3mm10 | #23 (H3.3) | AVIG | 32 (H3f3a) | mRNA | No | – | – | – |
H3mm11 | R2L, A25T (H3.3) | AAIG | 4 (H3f3a) | None | Yes | – | D3 | Local |
H3mm12 | K14N, A15S, E97G, Y99F (H3.3) | AAIG | 6 (H3f3a) | None | Yes | – | D1/2 | Local |
H3mm13 | A29V, R69G, R131C (H3.3) | AAIG | 4 (H3f3a) | mRNA | Yes | – | D1/2 | Local |
H3mm14 | #37 (H3.3) | AAIG | 89 (H3f3a) | mRNA | No | – | – | – |
H3mm15 | L100Q, I112V, R128C (H3.3) | AAIG | 5 (H3f3a) | mRNA | No | – | – | – |
H3mm16 | R8H, Q19K, R128C, G132R (H3.3) | AAIG | 7 (H3f3a) | None | Yes | – | D1/2 | Local |
H3mm17 | #16 (H3.3) | SAIG | 24 (H3f3a) | mRNA | No | – | – | – |
H3mm18 | #12 (H3.3) | AAIG | 17 (H3f3a) | None | No | – | – | – |