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Fig. 5 | Epigenetics & Chromatin

Fig. 5

From: Role of Ccr4-Not complex in heterochromatin formation at meiotic genes and subtelomeres in fission yeast

Fig. 5

Effect of ccr4 catalytic mutations, and of not2 and mot2/not4 inactivation, on heterochromatin integrity of islands and subtelomeric regions. Enrichment in H3 or H3K9-me2 in heterochromatin islands determined using ChIP-seq. The y axes show the normalized enrichment in the indicated immunoprecipitate and the x axes correspond to the position along the chromosome. Data are shown for wild-type cells and for the indicated mutants. a mei4 locus in wild-type, ccr4-D558A and ccr4-H665A. b Right subtelomere of chromosome 2 in wild-type, ccr4-D558A and ccr4-H665A. c mei4 locus in wild-type, not2Δ and mot2/not4Δ. d Right subtelomere of chromosome 2 in wild-type, not2Δ and mot2/not4Δ.

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Epigenetics & Chromatin

ISSN: 1756-8935