Fig. 3
From: Wanderer, an interactive viewer to explore DNA methylation and gene expression data in human cancer
DNA methylation and gene expression of PTGIS. a DNA methylation profile of PTGIS CpG island in colon adenocarcinomas (COAD) and prostate adenocarcinomas (PRAD). Note that cg1077290 probe (denoted by an arrowhead) is already very methylated in colon normal tissue, offering poor discriminative resolution to detect tumor hypermethylation compared with the rest of CpG island probes (labeled in green). In contrast, this probe (cg1077290) shows the highest level of hypermethylation in prostate cancers (PRAD) and remains unmethylated in normal tissue, resulting as the most discriminant variable in this type of cancer. b Overall gene expression of PTGIS gene in colon and prostate samples