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Figure 2 | Epigenetics & Chromatin

Figure 2

From: A balancing act: heterochromatin protein 1a and the Polycomb group coordinate their levels to silence chromatin in Drosophila

Figure 2

HP1a affects levels of H3K27me3 and H3K4me3. (A-C) H3K27me3 levels in 1–3 h embryos from (A) Su(var)2-5 05 /CyO, (B) E(z) 731 /TM6, and (C) Su(z)12 4 /TM6 parents at promoters of Ubx, hb, Sxl, nullo, bnk, h, tsr, sgs8, cta, and lt. All NI data is significantly below the lowest ChIP signal. (D) H3K4me3 levels 1–3 h embryos from Su(var)2-5 05 /CyO parents at same promoters. Asterisks show significant changes relative to Ore R (*P value <0.05, **P value <0.005, ***P value <0.0005). Error bars represent ± SEM. H3K27me3, trimethylated histone H3 at lysine 27; NI, non-immune; Sxl, Sex-lethal; Ubx, Ultrabithorax; hb, hunchback; tsr, twinstar; bnk, bottleneck; h, hairy; lt, light; cta, concertina.

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