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Figure 3 | Epigenetics & Chromatin

Figure 3

From: Occupancy by key transcription factors is a more accurate predictor of enhancer activity than histone modifications or chromatin accessibility

Figure 3

Contributions of TF binding versus histone modification enrichment to enhancer activity. (A) Distributions of enhancer activities of 273 DNA segments marked by each feature individually. The asterisks indicate statistically significant difference in activity between the presence and absence of the features. (B) Proportions of DHSs in 24-h-induced G1E-ER4 cells (total of 93,705) and tested DNA fragments that overlap DHSs (total of 188) with each feature combination. (C) The percentage of active enhancers captured by each set of features and the success rate of tested DNA segments (total of 273) with each feature combination.

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Epigenetics & Chromatin

ISSN: 1756-8935