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Figure 3 | Epigenetics & Chromatin

Figure 3

From: Drosophila Cyclin G and epigenetic maintenance of gene expression during development

Figure 3

CycG genetically interacts with Asx. (A, B) Effect of CycG misregulation on the penetrance of ectopic sex combs on L2 induced by (A) Asx XF23 and (B) Asx 3. (C, D) Penetrance of A4 to A5 (C) and A5 to A4 (D) abdominal segment transformations in Asx 3/+, Asx 3/+;da > CycG RNAi and Asx 3/+;da > CycG ΔP/+ males. (E) Posterior abdomens of adult males showing wild-type male pigmentation in A4 to A6, A4 to A5 transformation in Asx 3/+ male (black arrowhead), and A5 to A4 transformation in Asx 3/+;da > CycG ΔP/+ male (white arrowhead). Fisher’s exact test, *P < 0.01 **P < 0.0001 (n ≥ 30). L2: mesothoracic leg. A4, A5, A6: abdominal segments 4, 5, and 6.

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