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Figure 3 | Epigenetics & Chromatin

Figure 3

From: DNA demethylation by 5-aza-2′-deoxycytidine is imprinted, targeted to euchromatin, and has limited transcriptional consequences

Figure 3

Limited transcriptional consequences of 5-aza-CdR-mediated genomic demethylation. We show protein-coding (a) and long non-coding RNA (b) genes to have very limited proportions of genes that are up-regulated (green) or down-regulated (red) in exposed or recovered cells. The proportion of genes in each situation is indicated. The x axis in each case is control cells not exposed to 5-aza-CdR at that time point. FPKM, fragments per kilobase per million reads; lncRNA, long non-coding RNA; 5-aza-CdR, 5-aza-2′-deoxycytidine.

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Epigenetics & Chromatin

ISSN: 1756-8935